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JMD 2004, Vol. 6, No. 2
Copyright © 2004 American Society for Investigative Pathology & Association for Molecular Pathology

Consultations in Molecular Diagnostics

A Novel Streptococcus Organism Identified in a Case of Fulminant Endocarditis Using 16S rDNA Sequencing

Zsolt Jobbagy^*, Claire B. Fabian, Vincent A. Memoli^* and Joseph D. Schwartzman^*

From the Department of Pathology, * Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire; and the Department of Pathology, The Cheshire Medical Center, Keene, New Hampshire

Abstract

We report the identification of a virulent Streptococcus organism associated with fulminant endocarditis, using 16S rRNA gene amplification, sequencing and assembly from formalin-fixed, paraffin-embedded archival heart valve tissue, years after the autopsy of a patient.

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