JMD Association for Molecular Pathology 2008 Annual Meeting
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Originally published online as doi:10.2353/jmoldx.2008.080019 on April 10, 2008

Published online before print April 10, 2008
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Journal of Molecular Diagnostics 2008, Vol. 10, No. 3
Copyright © 2008 American Society for Investigative Pathology & Association for Molecular Pathology
DOI: 10.2353/jmoldx.2008.080019

Commentary

Nucleophosmin (NPM1) Mutations in Acute Myeloid Leukemia: An Ongoing (Cytoplasmic) Tale of Dueling Mutations and Duality of Molecular Genetic Testing Methodologies

Gerald Wertheim and Adam Bagg

From the Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

Abstract

This Commentary highlights two articles that focus on molecular techniques to identify mutations in nucleophosmin (NPM1), which is the most frequently mutated gene in cytogenetically normal acute myeloid leukemia (CN-AML)






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Copyright © 2008 by the American Society for Investigative Pathology and the Association for Molecular Pathology.